Description

Buy NAD+ Online

Nicotinamide Adenine Dinucleotide (NAD+) is a fundamental coenzyme central to cellular bioenergetics, DNA repair, and epigenetic regulation. As a critical component in redox reactions, NAD+ facilitates metabolic processes and serves as a substrate for key enzymatic families including sirtuins and PARPs . For the European research community, sourcing high-purity NAD+ is paramount to ensuring experimental validity and reproducibility.

At eupeptideshop.org, we cater exclusively to the rigorous demands of laboratory professionals. We offer premium NAD+ for research purposes, ensuring compliance with EU standards for research chemicals. Whether you are conducting studies in mitochondrial biology, aging, or neurodegeneration, our NAD+ provides the consistency required for advanced in vitro and in vivo models.

Technical Specifications

To maintain the highest standards of scientific integrity, we provide exhaustive analytical data for all our products. Researchers across Germany, France, and the Netherlands rely on our detailed specifications for their experimental protocols.

• Molecular Formula: C21H27N7O14P2

• Molecular Weight: 663.43 g/mol

• CAS Number: 53-84-9

• Purity: ≥98% (HPLC)

• Appearance: White to off-white powder

• Solubility: Soluble in water (50 mg/mL or higher). It is recommended to prepare stock solutions in sterile, deionized water.

• Stability: Lyophilized powder is stable for 2 years when stored at 4°C. For long-term storage (up to 3 years), storage at -20°C is recommended.

• Storage Conditions: Store lyophilized material desiccated, protected from light and moisture, at -20°C. Avoid repeated freeze-thaw cycles once reconstituted.

Reconstitution and Handling Protocols

Proper handling of research peptides is essential to maintain bioactivity. For NAD+, the following guidelines are recommended to ensure accurate assay results.

1. Preparation of Stock Solutions: Calculate the required volume of solvent (sterile water or PBS) to achieve the desired molar concentration. Allow the vial to equilibrate to room temperature before opening to prevent moisture absorption.

2. Reconstitution: Gently add the solvent to the inside wall of the vial. Swirl gently; do not vortex, as this can cause denaturation or foaming.

3. Aliquoting: Due to the instability of NAD+ in solution to repeated freeze-thaw cycles, aliquot the reconstituted peptide into sterile, low-binding microcentrifuge tubes.

4. Storage of Solutions: Store aliquoted solutions at -80°C for up to 6 months. Avoid storage at -20°C for extended periods once in solution.

Research Applications

NAD+ is not merely a metabolic cofactor; it is a signaling molecule that modulates cellular aging and stress responses. Recent clinical trials highlighted in Nature Aging emphasize the therapeutic potential of targeting NAD+ metabolism in neurodegenerative diseases and age-related decline . Key research applications include:

• Sirtuin Activation Studies: Investigating the role of NAD+-dependent deacetylases in caloric restriction and longevity.

• Mitochondrial Bioenergetics: Measuring oxidative phosphorylation and ATP synthesis in isolated mitochondria.

• DNA Repair Mechanisms: Evaluating PARP (Poly ADP-ribose polymerase) activity in response to genotoxic stress.

• Neurodegeneration: Modeling axonal degeneration and exploring neuroprotective strategies, particularly involving SARM1 pathways.

Safety and Compliance

NAD+ is strictly intended for research use only (RUO) and is not for human consumption or clinical use . Researchers should adhere to institutional safety protocols, including the use of appropriate personal protective equipment (PPE) such as gloves and lab coats. While NAD+ precursors are marketed as supplements in consumer retail, our product is a high-purity chemical reagent designed for laboratory investigation .

High-Intent FAQ for Sales Conversion

1. Where can I buy high-purity NAD+ online for research in Europe?
For guaranteed purity and EU compliance, you can buy NAD+ online directly from eupeptideshop.org. We supply research laboratories across the EU with verified peptides and research chemicals.

2. What is the purity of NAD+ sold at eupeptideshop.org?
We guarantee a minimum purity of 98% as verified by High-Performance Liquid Chromatography (HPLC). This ensures reliable and reproducible data for your sensitive assays.

3. Do you ship NAD+ peptides to Germany, France, and the Netherlands?
Yes. We specialize in fast, discreet, and reliable shipping of laboratory peptides throughout the EU, including Germany, France, Spain, and the Netherlands. Our logistics are tailored for research chemicals.

4. What is the molecular weight of NAD+?
The molecular weight of Nicotinamide Adenine Dinucleotide (NAD+) is 663.43 g/mol, with a molecular formula of C21H27N7O14P2. This data is crucial for molarity calculations in your experiments.

5. Is this NAD+ product the same as consumer NAD+ supplements?
No. Our NAD+ is a high-purity reagent for research use only. It is not a dietary supplement. Consumer products, like those found in retail stores, contain different formulations and excipients not suitable for controlled laboratory research.

6. How should I store NAD+ peptide upon arrival?
Store the lyophilized powder desiccated at -20°C, protected from light. Upon reconstitution, aliquot and store at -80°C to avoid degradation from freeze-thaw cycles.

7. What are the main research applications for NAD+?
NAD+ is primarily used in research concerning cellular energy metabolism, mitochondrial function, aging (sirtuin pathways), and neurodegeneration (specifically regarding axonal degeneration and SARM1 activity).

8. Can I get a Certificate of Analysis (CoA) for NAD+?
Yes. We provide comprehensive Certificates of Analysis for all our products, detailing purity levels and batch-specific data to ensure full traceability and quality assurance for your lab.

9. Is NAD+ soluble in water?
Yes, NAD+ is highly soluble in water. It is recommended to use sterile water or phosphate-buffered saline (PBS) for reconstitution to maintain stability.

10. What is the CAS number for NAD+?
The Chemical Abstracts Service (CAS) number for NAD+ is 53-84-9. You can use this number to cross-reference the chemical in scientific literature and databases. ........ .. ..  google