MOTS-c

Description

Buy MOTS-c Online | Mitochondrial-Derived Peptide for Research

In the rapidly evolving field of mitochondrial biology, the discovery of mitochondrial-derived peptides (MDPs) has opened new frontiers for scientific inquiry. Among these, MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) stands out as a compelling target for researchers investigating metabolic regulation, insulin sensitivity, and cellular aging. At eupeptideshop.org, we provide the European research community with access to premium-quality MOTS-c. As a trusted name among those who buy peptides EU, we ensure that your laboratory receives a product that meets the stringent demands of reproducible science.

If your research requires a peptide to investigate the AMPK pathway, glucose homeostasis, or exercise mimetics, knowing exactly where to buy MOTS-c online with guaranteed purity and reliable logistics is paramount. We bridge the gap between global peptide synthesis advancements and your laboratory bench across Europe.

Understanding MOTS-c: A Regulator of Metabolic Homeostasis

MOTS-c is a 16-amino acid peptide encoded within the mitochondrial genome, specifically the 12S rRNA region . Unlike nuclear-encoded peptides, MOTS-c’s origin in the mitochondria positions it as a primary signaling molecule in the communication between the mitochondria and the nucleus, a process known as retrograde signaling. Primary research indicates that MOTS-c plays a significant role in regulating metabolic processes under conditions of energetic stress .

The primary mechanism of action attributed to MOTS-c is the activation of the AMP-activated protein kinase (AMPK) pathway . By mimicking a state of cellular energy deficit, it promotes glucose uptake and increases insulin sensitivity, making it a peptide of high interest for metabolic research peptides EU studies. Furthermore, recent clinical studies have explored circulating MOTS-c levels as a potential biomarker for cardiovascular health, highlighting its systemic relevance .

Product Specifications: The Gold Standard for Research

When you decide to buy MOTS-c online from eupeptideshop.org, you are acquiring a reagent that adheres to the highest analytical standards. We understand that impurities can skew data; therefore, we provide comprehensive batch-specific data to ensure your experimental validity. As a premier peptide supplier Spain and across the EU, our specifications are designed to match those of global reagent leaders .

• Molecular Information

  • Synonyms: Mitochondrial Open Reading Frame of the 12S rRNA-c, MOTS-c (human)

  • Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂

  • Molecular Weight: 2174.60 g/mol (base)

  • CAS Number: 1627580-64-6

  • Purity Specifications: ≥99% (as determined by HPLC). Our quality control ensures a purity profile suitable for advanced in-vitro and in-vivo research models, exceeding the standard >95% threshold .

  • Sequence Information: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH (human sequence) .

• Handling & Stability

  • Appearance: Sterile, lyophilized (freeze-dried) white powder.

  • Solubility Profile: MOTS-c is readily soluble in water. For stock solutions, it is recommended to use sterile water for injection or PBS. As noted in chemical inventories, solubility in DMSO may be limited, and aqueous solvents are preferred to ensure complete reconstitution .

  • Storage Recommendations:

    • Lyophilized Powder: Stable for up to 36 months when stored at -20°C, protected from light .

    • Reconstituted Solution: Aliquot and store at -20°C or -80°C. Avoid repeated freeze-thaw cycles. Under proper storage (-80°C), aliquots can remain stable for up to 6 months . Short-term storage (up to one month) is acceptable at 2-8°C .

  • Stability Data: The lyophilized form exhibits minimal degradation (<5%) when stored under recommended conditions. Peptide integrity should be verified via mass spectrometry if stored for extended periods post-reconstitution .

Research Applications and Known Citations

The body of knowledge surrounding MOTS-c is expanding, particularly concerning metabolic and age-related diseases. Researchers who buy research peptides EU grade MOTS-c typically investigate the following areas:

• Metabolic Regulation: Studies demonstrate that MOTS-c can activate AMPK and increase the expression of GLUT4, facilitating glucose clearance and offering a model for studying insulin resistance and obesity . It has been shown to prevent high-fat diet-induced obesity in murine models .

• Cardiovascular Research: Recent 2024 cohort studies have identified circulating MOTS-c as a significant variable in predicting cardiovascular events and mortality in specific patient populations, suggesting its role as a potential biomarker for cardiac stress .

• Osteogenic Differentiation: In vitro research indicates that MOTS-c promotes the differentiation of bone marrow mesenchymal stem cells (BMSCs) into osteoblasts, implicating its role in bone metabolism and potential models for studying osteoporosis .

• Aging and Longevity: As an MDP, MOTS-c is studied for its role in mitigating age-related physical decline and maintaining muscle homeostasis .

Proper Handling and Reconstitution Protocols

To maintain the integrity of our high purity peptides Germany researchers trust, strict adherence to aseptic technique is required. While we supply the reagent for research use only, the following protocols are standard in the field.

Reconstitution Guidelines:

1. Preparation: Calculate the desired concentration. A common stock concentration is 1 mg/mL or 5 mg/mL.

2. Method: Using a sterile insulin syringe, inject the appropriate volume of cold, sterile water or sterile PBS into the vial .

3. Mixing: Direct the solvent against the inner wall of the vial. Do not forcefully jet directly onto the lyophilized cake. Do not vortex. Swirl the vial gently until the peptide is fully dissolved. If necessary, allow the vial to sit for a few minutes to facilitate dissolution.

4. Aliquoting: To avoid damage from repeated freeze-thaw cycles, immediately aliquot the reconstituted solution into sterile, low-protein-binding tubes.

Safety Considerations:

• For Research Use Only: Not for human consumption or clinical use. Not for veterinary use.

• Handling: Use personal protective equipment (gloves, lab coat, safety goggles). Work under a laminar flow hood (Class II biological safety cabinet) to maintain sterility.

• Disposal: Dispose of any unused material and sharps in accordance with your local institutional and EU regulations for biochemical waste.

Why Choose eupeptideshop.org to Source Your MOTS-c?

The European peptide market is crowded, but specificity and reliability set us apart. When you need to buy peptides EU that match the quality found in major biochemical databases, our platform is your solution.

• Verified Purity: We provide access to certificates of analysis reflecting HPLC data, ensuring that what you order meets the >99% purity standard required for high-impact publications .

• Strategic EU Logistics: As a dedicated laboratory peptides Netherlands and peptide supplier Spain hub, we optimize shipping across the Schengen Area. Our inventory is housed within the EU, ensuring fast, compliant delivery without excessive customs delays.

• Research-Focused: Whether you are seeking GLP-1 research peptides EU for metabolic studies or specific mitochondrial peptides like MOTS-c, our catalog is curated for scientific advancement, not lifestyle use.

• Expert Support: Our team understands the nuance of peptide reconstitution and stability. We are here to ensure your order arrives intact and ready for your experiments.

Elevate your research on metabolic pathways and mitochondrial function. Visit eupeptideshop.org today to buy MOTS-c online and experience the difference that true high-purity reagents make.

 FAQ: Buy MOTS-c Online

Q1: Where can I buy MOTS-c online in Europe with next-day delivery?
A: You can securely purchase MOTS-c from eupeptideshop.org. We ship from our EU warehouse (Netherlands/Spain) to ensure fast delivery to Germany, France, and the UK. We are a leading peptide supplier Spain network offering rapid fulfillment.

Q2: Is this MOTS-c the same high purity used in published studies?
A: Yes. Our MOTS-c meets rigorous standards with ≥99% HPLC purity, aligning with the quality used in major studies cited on PubMed and available from top-tier reagent suppliers . We provide access to purity data for your verification.

Q3: Do I need a prescription or special license to order research peptides for my lab in France?
A: No prescription is needed for peptides for research France as they are sold for laboratory use only. By ordering from eupeptideshop.org, you confirm that you are a qualified researcher and that the products will be used for in-vitro or licensed in-vivo research, in compliance with research chemicals EU compliant standards.

Q4: What is the minimum order quantity for MOTS-c? Can I buy a small amount for initial testing?
A: We understand the need for pilot studies. You can purchase single vials of MOTS-c to validate your assays before committing to larger quantities. Our platform is designed for flexibility for laboratory peptides Netherlands and beyond.

Q5: How does eupeptideshop.org ensure product integrity during shipping to Germany?
A: We ship our high purity peptides Germany researchers require in insulated packaging to maintain stability during transit. Lyophilized peptides are shipped at ambient temperature, as they are stable for several days, with immediate storage at -20°C upon receipt advised .

Q6: Is the payment process secure for international peptide orders?
A: Absolutely. Our ecommerce platform uses bank-level encryption to protect your transaction. We offer secure payment methods tailored for buy peptides EU customers, ensuring your financial data and research interests remain confidential.

Q7: What if my vial appears to have lost vacuum? Is the peptide still good?
A: Our vials are sealed under strict conditions. If a vial appears compromised upon arrival, please contact us immediately. However, the lyophilized peptide is robust if stored correctly. Always check solubility; a clear solution upon reconstitution with water indicates the peptide integrity is intact. ........ .. ..  google